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Published in Diabetes Care showed that GLP-1 infusion reduced the gastric emptying rate of a solid meal by roughly 25% compared to saline in healthy volunteers ([1])
For most people, one of the first changes they observe is a shift in appetite
The good news is that there is no official contraindication to taking these medications together, and no direct pharmacological interaction has been established between semaglutide and bupropion
Researchers are now wondering if this could apply to things other than food and whether GLP-1s could reduce cravings associated with substance abuse
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