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They were removed from Category 2 in 2024 only because the nominations were withdrawn, not because they were judged safe
Females often pick mates based on their dominance in hopes the male will protect their young and pass down strong traits
It was the recurring theme in the discussion: patient demand for these therapies already exists
Future work should be focused and lean: enroll truly deficient, higher-risk patients, standardize formulations and dosing, and test event-driven hard endpoints aligned to mechanism, while embedding translational markers to confirm on-target biology
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