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A meta-analysis that combined the results of these two studies with those of six other prospective cohort studies found a significantly lower risk of coronary heart disease with higher intakes of dietary vitamin B 6 (RR, 0.81
Bischoff LJM, Kuijper IA, Schimming JP, Wolters L, Braak BT, Langenberg JP, et al
250(4): p
In addition to its effects on insulin, GIP plays a crucial role in fat accumulation by promoting the activity of adipocyte-expressed lipoprotein lipase and promoting bone formation by preventing osteoclast apoptosis, as evidenced by the thinner bone trabeculae seen in mice lacking GIP receptors [20,21,22]
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