Timing and administration Timing affects results more than most people realize
Additionally, the LEADER study reported a post-hoc analysis in patients with polyvascular disease (defined as atherosclerosis in two or more of the following vasculature territories: ocular, coronary arteries, cerebral arteries or arteries peripheral), in which they did not observe significant differences in the risk of non-fatal stroke in the liraglutide group versus placebo [63]
In addition, some non-coding RNAs, such as Bcl-2, Ago, MafA, Pdx1, MTPN, and caspase-3, etc., also play an important role in -cell apoptosis in T2DM patients by regulating the expression of key -cell factors (You et al., 2022)
Comparison of Glucagon-Like Peptide-1 Receptor Agonists and Thiazolidinediones on Treating Nonalcoholic Fatty Liver Disease: A Network Meta-Analysis