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Indeed recently it has been shown that dietary triglycerides appear to induce the secretion of GLP-1 via GPR40 in synergy with the Gs activating GPR119 (263)

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Whilst the prevalence of serious adverse pregnancy outcomes (major congenital anomaly, stillbirth and neonatal death) remains two to three times higher compared with the general maternity population and can affect up to one in ten unplanned pregnancies with higher HbA 1c , contemporary UK data are largely reassuring (Fig