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Abstract:Chronic hyperglycemia in diabetics causes microvascular damage through four mechanisms of biochemical changes, including activated protein kinase C (PKC) pathway, activated hexosamine pathway, increased polyol pathway, and increased advanced glycation end-products (AGEs), all of which will increase Reactive Oxygen Species (ROS) levels
What glutathione therapy may address is the underlying environment that makes airways reactive in the first place
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This means the FDA recognizes that AOD 9604 is safe under conditions of intended use
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