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The primary cellular targets include other radical species such as to form peroxynitrite, oxygen to form NO 2 and metalloproteins as those containing haems and ironsulfur clusters

In the context of animal health, SOD-mediated antioxidant defense is essential for maintaining normal cellular metabolism

Theyre kind of disadvantaged in multiple ways already and this is just one more way, said Wedad Rahman, an endocrinologist with Piedmont Healthcare in Conyers, Georgia

We therefore investigated the predictive value of these variables in our cohort, after adjusting for the non-genetic factors described above (Supplementary Information)