Because of the potential for these chemicals to bind to oestrogen receptors, it was hypothesised that they could potentially stimulate the growth of ER+ breast cancers 31, 32
Avoid drinking large volumes during meals, as this fills your stomach and worsens early satiety and nausea
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Ongoing monitoring may include follow-up appointments (for example, at 4, 8, and 12 weeks initially to coincide with dose escalation, then every 36 months) to assess: Weight loss progress and tolerability Gastrointestinal side effects and their management Cardiovascular parameters (heart rate, blood pressure) Nutritional adequacy and eating behaviours ADHD symptom control and medication effectiveness Mental health and overall wellbeing Patients should be advised to contact their healthcare provider if they experience: Severe or persistent abdominal pain, with or without vomiting (potential pancreatitis) Signs of dehydration or significant fluid loss Rapid or excessive weight loss Palpitations, chest pain, or shortness of breath Changes in mood or worsening of ADHD symptoms Right upper quadrant pain, fever, or jaundice (potential gallbladder disease) Any concerns about medication interactions Shared decision-making is essential