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Many people who follow a comprehensive protocol find that injecting in the morning on a rest day works best
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Nature communications, 11(1), 5205
In research models, this inhibition indirectly preserves NAD by reducing methylation of nicotinamide, and also maintains SAM levels an effect precursors do not address
Some medications can also affect absorption of Vitamin B12 in the gut, and B12 deficiency can be an issue if you have had weight loss surgery
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