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Evidence From Clinical Literature and Real-World Practice Major weight loss trials for semaglutide (STEP 1-4 studies) achieved average weight reductions of 10-22% body weight over 68 weeks without phentermine combination, demonstrating robust monotherapy efficacy
Reserve stimulant laxatives for the short term only, and get urgent care if you develop: Severe abdominal pain Vomiting Inability to pass gas When To See Your Clinician Immediately Go to your provider or emergency care for severe dehydration, prolonged vomiting, abdominal distension that worsens, or hiccups that prevent eating or breathing
Table 17: Detailed Breakdown of the CADTH Reanalyses of the BIA BIA = budget impact analysis
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