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Because these agents slow gastric emptying, they can affect absorption of other oral medications, and their use in pregnancy, breastfeeding, or with certain gastrointestinal conditions requires specific guidance

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The triple-receptor approach extends the metabolic research effects of single-receptor (semaglutide) and dual-receptor (tirzepatide) predecessors by adding glucagon receptor activity which contributes to additional metabolic and energy expenditure pathways

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