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OA is a complex disease influenced by various factors including the natural aging process, gender, genetic predisposition, obesity, and physical factors (e.g., joint trauma and injury) 5
PMCID: PMC10534984
In clinical practice, side effects often depend on the starting dose, how quickly the dose is increased, meal size, hydration, and sensitivity to delayed stomach emptying
Paracetamol is effective for headaches, musculoskeletal pain, and fever, though it lacks the anti-inflammatory properties of NSAIDs
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