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The peptide has been studied extensively across various organ systems, demonstrating cytoprotective effects in the gastrointestinal tract, liver, pancreas, heart, blood vessels, muscle, tendon, ligament, bone, and nervous system
Health authorities discourage its use due to insufficient human safety data, and some jurisdictions have restricted it as a prescription-only medicine despite it not being available through legitimate prescriptions
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List of medicines under additional monitoring European Medicines Agency
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