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However, a closer examination of the propolis-alone group revealed certain statistically significant differences in reproductive hormones (decreased LH, testosterone, and E2) and sperm parameters (decreased percentages of dead, live, normal, abnormal, and motile sperm) compared to the control group

CD38: targeted therapy in multiple myeloma and therapeutic potential for solid cancers

Pro-inflammatory mediators such as TNF-, IL-1, and IL-17A enhance SMCs responsiveness to growth factors by upregulating PDGFR expression, thereby promoting SMC proliferation and contributing to intestinal wall thickening and fibrosis 85

Start: Begin at 500 mcg once daily to gauge tolerability