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In bovine cumulusoocyte complexes, the peptide not only activated telomerase but also enhanced TERT protein localization, a key driver of telomere repair during early development [15]
As understanding of tumor heterogeneity deepens, selecting and prioritizing combination strategies tailored to specific TME profiles such as tumors with high MDSC infiltration or varying levels of PD-L1 expression will be critical for advancing cancer immunotherapy
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