It means that as a standalone oral therapy at the tested doses, it did not produce the magnitude of weight loss that pharmaceutical companies require for commercial viability
CrossRef The economic burden of cancers attributable to smoking in Korea, 2014 Thi Nguyen, Minji Han, Jin-Kyoung Oh Tobacco Induced Diseases.2019;[Epub] CrossRef Incidence and Mortality Rates of Second Pancreatic Cancer Among Survivors of Digestive Cancers Hyeong Sik Ahn, Tae Uk Kang, Heather Swan, Min Ji Kang, Nayoung Kim, Hyun Jung Kim, Seon Mee Park Pancreas.2019
As discussed throughout this article, Epitalon remains an experimental compound
MDM2 mediates the ubiquitin-dependent degradation of SPY1, resulting in a downregulation of SPY1 expression, which in turn upregulates the expression of ALOX15 and growth differentiation factor 15 (GDF15), while decreasing the levels of GCH1, GPX4, and GSH