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This lipid accumulation leads to mitochondrial dysfunction, which in turn exacerbates HF 41
The NEJM study found that patients reported significant improvements on their sleep scores
Tirzepatide is administered as a once-weekly subcutaneous injection, with a recommended starting dose of 2.5 mg once weekly for 4 weeks, then increasing by 2.5 mg every 4 weeks until the target dose (up to 15 mg) is reached
2013;116(4):e24754
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