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Food and Drug Administration (FDA) in 2021 for chronic weight management in adults and children 12 and older with obesity (BMI of 30 or more) and for adults who are overweight (BMI of 27 or more) with one or more weight-related health conditions, such as type 2 diabetes or high blood pressure
This was associated with the onset of metabolic disorders at an early stage, including insulin resistance, increased triglyceride levels and elevated leptin levels
References Wilding, J
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