Several factors can contribute to hyperpigmentation, such as long hours under the sun (leading to sun spots), acne scars from previous breakouts, and hormonal changes that are often seen during pregnancy or using birth control
Moreover, other active ingredients of Chinese medicine, including wogonoside (WG), isoliquiritigenin (ISL), decursin, and chrysophanol, exert their antihepatic fibrosis efficacy by inducing HSCs ferroptosis
Comparatively, folate deficiency is notably prevalent in cases of depression, occurring twice as often as vitamin B12 deficiencies (20, 21, 30, 64)
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