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Presented for research literature review only Yamamoto K et al
The enzyme is expressed at high levels in red blood cells, which are easy to isolate and analyze, and the only vitamin-derived cofactor it requires is TPP
Your doctor may: Monitor serum B12 levels Evaluate homocysteine and methylmalonic acid (MMA) Check complete blood count (CBC) Assess for symptom improvement (fatigue, cognitive clarity, neuropathy) Symptoms like improved energy, mood, and focus typically appear within days to weeks
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