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Description

In clinical trials, participants who took 2 grams per day for a year, or 4 grams per day for around two months, showed no adverse effects

Paradoxically, despite greater potency, tirzepatide's GIP component may reduce nausea compared to semaglutide at equivalent effect levels

(49) revealed that GLP-1 agonists significantly reduced the risk of HF in patients with T2D (RR 0.89, 95% CI 0.82 to 0.98), whereas Qin and Song (50) reported that they reduced the risk of nonfatal stroke (RR 0.85