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(1994) Liver transplantation for Wilson's disease: indications and outcome
Clin Gastroenterol Hepatol 2008
reported in approximately 4060% of participants in higher-dose groups [1] Vomiting reported in approximately 2030% of participants at higher doses Diarrhoea Constipation Decreased appetite (which, whilst contributing to weight loss, can also be uncomfortable) The majority of gastrointestinal events were mild to moderate in severity and tended to diminish over time as participants adjusted to the medication
When NNMT activity is inhibited, these methyl donors become available for other methylation reactions in the body
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