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Nicotinomide (vitamin B3) has been shown to be liver toxic in doses over 3G per day
PMID: 32928579
Your system simply flushes out whatever it doesnt need
Anal Bioanal Chem 407:23012309 Kou S, Chen L, Tu W, Scossa F, Wang Y, Liu J, Fernie AE, Song B, Xie C (2018) The arginine decarboxylase gene ADC 1, associated to the putrescine pathway, plays an important role in potato cold-acclimated freezing tolerance as revealed by transcriptome and metabolome analyses
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