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The combination of this particular class with thiazolidinediones presents an interesting concept, currently under trial in a phase-4, open-label study, where empagliflozin is being evaluated alone and in conjunction with pioglitazone on diabetic patients, with the primary outcome being the measurement of liver fat content by MRI-PDFF (NCT03646292)

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Plants [edit] In higher plants, superoxide dismutase enzymes (SODs) act as antioxidants and protect cellular components from being oxidized by reactive oxygen species (ROS)