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Payers deny retroactive claims that lack authorization on file, with no appeal recourse

Those with severe alcohol use disorder should seek established treatment approaches and discuss any interest in GLP-1 medications with addiction medicine specialists

The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight