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Two Phase 3 clinical trials, RECONNECT 1 and RECONNECT 2, enrolled more than 1,200 premenopausal women and demonstrated its effectiveness
If reliable refrigeration isnt available during travel, reconstitute only single doses immediately before use and transport remaining peptide in unreconstituted lyophilised form, which tolerates ambient temperature without degradation
Treatment of rats with roridin E caused minimal toxicity on the hepatic and renal tissue, however, co administration of linoleic acid with roridin E resulted in increase toxicity due to increased incorporation to the cell membrane or inhibit its biotransformation [159]
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