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Where the anaesthesia exceeded 30 min (ICP monitoring and ventriculo-cisternal perfusion), surgical tracheotomy and mechanical ventilation were employed using the VentElite system (Harvard Apparatus) to ensure stable respiratory partial pressure of carbon dioxide (pCO 2 ) and arterial oxygen saturation, and thus stable plasma pH and electrolyte content
For patients with a history of pancreatitis, special caution should be exercised when using it
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Retatrutide has shown excellent glycemic improvement in its trials as well, and its GIP and glucagon receptor activity may offer additional benefits for insulin sensitivity that GLP-1-only drugs cannot match
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