Spermatozoa are susceptible to oxidative stress due to a lack of their own cellular cytoplasmic antioxidants, high DNA susceptibility to oxidative damage, the presence of abundant polyunsaturated fatty acids (PUFAs) in their membrane, and high ROS production during their movements, generated by mitochondrial activity (18, 85, 89, 118)
By allowing for smaller doses, these plans help manage medication costs, which can be a significant barrier for many patients
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