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NA generated by gut microbes is also able to maintain a local NAD + /NAM pool that can be a source of circulating NA even in the absence of dietary precursor administration 126,127
These effects are usually temporary
GHK-based formulations, including nanoparticle conjugates, hydrogels, and clinical derivatives such as TriHex and TriHex 2.0, enhance fibroblast migration, ECM remodeling, collagen and elastin synthesis, and wound closure while providing antimicrobial activity
GHK-Cu promotes angiogenesis, the growth of new blood vessels, which theoretically could support tumor growth
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