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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

Starting with a modest dose to gauge bodily responses is prudent

However, many cats may benefit from B12 shot injections under their skin

Supports Healthy Metabolism Vitamin B12 plays a crucial role in how your body breaks down fats and carbohydrates for energy