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Interference of the p53-FOXO4 interaction resulted in selective apoptosis of senescent cells and restoration of tissue homeostasis in multiple mouse models
The levels of GSH was slightly reduced in MPP + -treated SHSY-5Y cells, which was further restored to baseline levels by Sp, together with accompanying decrease in accumulated GSSG (Fig
For instance, ROS can induce the formation of carbonyl groups on proteins, altering their structure and antigenicity
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