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The mechanosensitive ion channel PIEZO1 was found to be essential for the OPC detection of the elasticity of the ECM, and the knockdown of PIEZO1 resulted in increased proliferation and differentiation of OPCs in the aged CNS of mice (Segel et al., 2019)
Thats something to keep in mind when taking GLP-1, since the medication can cause muscle loss
If there is still no drop youll need to change the needle and check the flow once more
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