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GHK-Cu, a copper-binding tripeptide first isolated from human plasma by Pickart in 1973, is one of the most thoroughly studied peptides in skin biology, with published research demonstrating its influence on collagen synthesis, antioxidant enzyme regulation, and the expression of over 4,000 human genes
It plays a central role in cellular detoxification, the neutralisation of reactive oxygen species, and the regeneration of other antioxidants including Vitamins C and E
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