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Most users see darkening within 710 days , especially with some UV exposure
However, without direct head-to-head comparisons, treatment decisions rely on indirect evidence from heterogeneous trial populations, leaving optimal treatment choices uncertain
The Prime Therapeutics formulary for Texas plans (April 2026) places most generic antidepressants on Tier 1 (preferred generics) or Tier 2 (non-preferred generics), typically with no prior authorization required for first-line agents
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