Triggered by upstream signals, the initiator caspases undergo autocleavage, and the subsequently activated cleaved initiator caspases stimulate the downstream executioner caspases to execute apoptosis (106)
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first reported a polymorphism in GPx1, namely, a substitution at codon 198 of either proline (Pro) or leucine (Leu), Pro198Leu (SNP: 1050450), in lung cancer [87]