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About the study This phase IV trial was a multi-center, open-label study to evaluate the synergistic effects of Restylane Lyft or Contour in combination with Sculptra for cheek augmentation and correction of contour deficiencies, in patients experiencing facial volume loss following treatment with one of four brands of glucagon-like peptide-1 (GLP-1) receptor agonists

Here's the key part for digestive symptoms: they slow down how fast your stomach empties food into your small intestine

The medications are in a class called glucagon-like peptide-1 (GLP-1) therapies that mimic a natural gut hormone to help control blood sugar levels, slow digestion and increase feelings of fullness

4.2.6 Possible important contextual details pertaining to the study design and/or analysis The PICOS study design: This study does not have any perceivable adverse contextual details regarding the study design as this is a systematic review and a meta-analysis based on the Cochrane Organisation template for systematic review and meta-analyses