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On the other hand, in contrast to those enrolled in clinical trials, patients seen in routine clinical practice are allowed to switch between drugs within the same drug class, which could lower rates of treatment discontinuation
If gastrointestinal symptoms are severe or persistent, dose reduction or temporary treatment interruption may be necessary
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has shown minimal expression of L-carnitine synthesis pathway genes in human oocytes, and an absence of L-carnitine synthesis enzymes in cumulus cells (26)
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