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CPT-II on the inner membrane reconverts the acylcarnitine back to acyl-CoA for beta-oxidation
This dual action appears to amplify the overall GH, such as improved body composition, lipid profile, insulin sensitivity, and overall metabolic function in laboratory test models
There was no significant difference between the study groups before the intervention ( P = 0.35)
A current drawback of intracellular roGFP2-based mechanistic studies is, however, that the mechanisms and structure-function relationships still have to be validated in vitro
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