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they are often primary effects that are just as pronounced as the tanning

Initial Adjustment Period Nausea is most common during the initial weeks of treatment, particularly within the first 8 to 12 weeks

Key features include: Persistent right upper quadrant pain lasting more than six hours Fever and systemic signs of infection Tenderness in the right upper abdomen that worsens during deep breathing Jaundice (yellowing of skin and eyes) if bile duct obstruction occurs Dark urine and pale stools Loss of appetite and general malaise Some patients may experience chronic cholecystitis , characterised by recurrent episodes of milder abdominal discomfort, bloating, and intolerance to fatty foods

Over time, this might cause allergic reactions or reduced effectiveness as the body develops antibodies