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Factors affecting skin elasticity outcomes include age (younger individuals typically achieve better results), genetics (some people naturally produce more collagen), smoking status (smoking dramatically impairs collagen synthesis), hydration (well-hydrated skin remodels more effectively), and the rate and total amount of weight loss

This is concomitant with the histological findings of this study indicating bad impact of oxidative stress on testicular functions

Monitoring for common adverse effects allows for early intervention