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Cross-compound receptor-occupancy percentages are deliberately not compared here: occupancy (pRO) is a modeled inference, not a measurement, and Willard 2020 cautions that "calculating pRO values has caveats." These EC50s measure functional potency, not binding affinity
Yes, as long as you are using the same concentration calculation for all draws
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When weight loss is excessive or concerning, R63.4 (Abnormal weight loss) + Y42.3 should be documented alongside the primary diabetes code
They do not predict response to any specific medication, but they map the biology beneath the decision, context a telehealth prescription on its own never captures
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