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However, these are not actual GLP-1 drug patches and there is no strong clinical evidence that transdermal patches with these herbal ingredients can increase the bodys natural GLP-1 levels 3
Many researchers have focused on understanding the mode of action of inhibitors that can act differently depending on the DGF-in or DFG-out conformation
however, administration of retatrutide at higher doses significantly reduced circulating FGF21 levels, suggesting that retatrutide efficacy in MASLD is unlikely to be attributable to increased FGF21 levels
Given that retatrutide is not yet approved for clinical use in the UK, the most appropriate course of action for any woman interested in this treatment is to speak with her GP or a specialist in a Tier 3 or Tier 4 weight management service, or an endocrinology or diabetes team
