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Chronic neuroinflammation, driven primarily by sustained activation of microglia and astrocytes, contributes to the pathology of numerous CNS disorders (Kwon and Koh 2020

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Immunofluorescence analysis was performed with anti-Myc, anti-Tom20, and anti-Calnexin antibodies to visualize the localization of TurboID-MITOL, mitochondria, and ER, respectively

TERN is also initiating IND-enabling activities in 2023 for TERN-800, an oral GIPR modulator , with the intention of being used in combination with GLP1R agonists