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Patients in Austria and the UK were hospitalised after using counterfeit weight-loss pens, health authorities in both countries have said

While these effects initially made GLP-1 seem a promising candidate for drug development, the earliest clinical studies from 1992 and 1993 revealed that GLP-1s half-life in the body was disappointingly short

Through ongoing use and post-marketing experience, GLP-1 agonists have become better understood, with notable additional metabolic and cardiovascular benefits

Cost Considerations Brand-name dual agonists (Mounjaro/Zepbound) cost $1,069 monthly compared to $969 to $1,349 for pure GLP-1 agonists (Ozempic/Wegovy)