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Determination of Serum Homocysteine and Hypersensitive C-reactive Protein and Their Correlation with Premature Coronary Heart Disease
It is synthesized as a proreceptor that is cleaved into alpha and beta chains and assembled into a covalent heterotetramer, two alpha subunits and two beta subunits held together by disulfide bonds, which sits in the membrane as a preformed dimer even in the absence of ligand
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However, they determined that the strength of the evidence for these associations was limited, and some of the studies did not adequately correct for potential confounders such as the severity of depression, hormone levels, and lifestyle factors, among other variables
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