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Synaptic functionality of these synapses was demonstrated via the presence of analog-induced spinogenesis, and the colocalization of synaptic markers in newly formed dendritic spines which were coupled with enhanced miniature excitatory postsynaptic currents
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Mechanistic Research Perspective Regulation of neural cellular signaling pathways Modulation of gene expression associated with circadian rhythms Influence on mitochondrial energy balance within neural cells Interaction with stress-responsive peptide networks Analysis of peptide signaling integration in neural and endocrine systems Primary Research Applications Neurochemical Signaling Analysis: Used in experimental models studying neurotransmitter pathways and peptide-mediated neural communication
Further, well-designed clinical studies are needed to confirm the efficacy and safety of both peptides in clinical practice
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