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This trial enrolled adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, and evaluated multiple doses of retatrutide against placebo over 48 weeks
For injectable GLP-1 medications: Timing requirements : For once-weekly injections (semaglutide [Ozempic, Wegovy], dulaglutide [Trulicity], exenatide extended-release), administration can occur at any time of day, with or without food
They even appear to help individuals quit smoking
Primary Uses in Diabetes and Obesity Management Originally developed for the treatment of type 2 diabetes, GLP-1 agonists have proven effective in promoting weight loss, making them valuable in obesity management as well
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