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Each herbal extract used in this study was obtained using a standard method described as follows: each herbal medicine (purchased from Tochimoto Tenkaido (Osaka, Japan)) was extracted in water (10-times volume of herbal medicine) at 100 C for 50 min, evaporated under reduced pressure, and freezedried to obtain a powder extract
This protocol details a daily subcutaneous injection regimen for 20 days, followed by an extended break
Almengl C, Devesa P, Devesa J, Arce VM
The STEP 1 trial used 2.4 mg as the target maintenance dose and achieved average weight loss of 14.9% of body weight over 68 weeks
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