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It boosts the skin defence systems, microbiota and barrier function

(And while slightly increasing GLP-1 levels wont result in extreme weight loss, you certainly dont want to cause them to nosedive, either.) A 2023 study found that folks with a misaligned circadian rhythm (due to factors like night shift work or insomnia) tend to have a low GLP-1 response and a high risk of insulin resistance and obesity (18)

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Orlistat causes gastrointestinal effects (oily stools, flatulence) but only when dietary fat is consumed