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Cardiometabolic improvements across published trials include reductions in blood pressure, triglycerides, LDL-cholesterol, HbA1c, and fasting glucose
Spatially resolved metabolomics has uncovered region-specific metabolic changes in diabetic kidneys, such as altered glycolysis, dysregulated lipid metabolism, and imbalances in redox and osmotic homeostasis, each occurring in distinct regions (22)
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